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Max Görlitz's avatar

Thanks for this article! I knew almost nothing about LED development so this was interesting.

A few points of feedback:

>experts now estimate there is a 1 in 8 chance of a pandemic killing over 90 million people by 2050

Fairly bold claim so would be good to link to a source.

> typically between 207 and 222 nanometers (nm)

There is no one definition but I have most often seen far-UVC defined as 200-235 nm.

> and the tear film of the eye

I think this is slightly misleading because AFAIU, the tear film does absorb a little bit but really not that much. See e.g. from the Blueprint report: "Additionally, a study suggests that the tear film transmits >90% of farUVC wavelengths between 220–230 nm and that 222-nm doses as low as 3 mJ/cm² lead to reduced viability of cultured human corneal epithelial cells, despite overlay with human tears or tear substitutes of equal protein composition and thickness as in vivo tears60. One caveat is that in vitro studies do not always replicate in vivo studies due to the difficulty in replicating an intact tear film containing all three layers. However, physics (Beer’s Law) suggests that the tear film will absorb little far-UVC, given its known thickness and known average protein concentration. Some therefore posit that the tear film provides little protection and most farUVC reaches the outermost epithelial cell layers, where it is absorbed primarily by the proteins in those cells but will also cause some amount of DNA damage. In contrast, the stratum corneum in the skin is de-nucleated, making it impossible for DNA damage to occur in those cells where the majority of far-UVC is absorbed."

> rely on perfect air circulation to do their job

I might be wrong but I think for upper-room GUV to work well, air circulation doesn't need to be "perfect", it only needs to be good enough. As far as I remember, a simple air circulator fan in the room is sufficient for well mixed air conditions. In general, upper-room GUV is a well-established and effective technology IF (!) implemented correctly.

> The light produced is also very precise, a high-quality LED’s peak wavelength is accurate to within ±2.5 nm of its target. This precision is extremely important for Far-UVC, where the safety window is a very narrow range centred around a wavelength of 222 nm.

The safety window being fairly narrow is true but the ±2.5 nm in the previous sentence by association makes it sound a bit like the safety range was 222 nm ±2.5 nm but really the range of 200-235 nm seems pretty safe as far as I know.

Sorry for nitpicking, I think the article is very useful overall! Fingers crossed we get far-UVC LED soon!

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